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Advancing the Science Webinar Series:
Chemical-Induced Asthma

The Role of Toxicology in Asthma Hazard Assessment

April 28, 2016
Webinar was recorded and is available to registrants.
Dr  David Basketter
Dr. David Basketter

A review of the in vivo, in vitro, and in silico models used for toxicological assessments of asthma and surrogate or related endpoints, specifically their utility and limitations. This speaker will also discuss new methods, tests, and approaches for toxicological assessment.

Learning Objectives:

  • To discuss in vivo, in vitro, and in silico models for testing asthma and surrogate or related endpoints
  • To discuss the types of reliable, human relevant information that these models provide
  • To discuss the limitations of these models when considering their use for human health hazard assessment

Dr. David Basketter is a Eurotox Registered Toxicologist and a Fellow of the Royal Institute of Biology, the Royal College of Pathology, the British Toxicology Society, the Royal Society of Medicine, and the Academy of Toxicological Sciences. He previously worked at the Unilever Safety Laboratory on allergy and irritation and is the past President of the European Society of Contact Dermatitis. He is the chair of committees on irritation and allergy topics, including European trade associations for cosmetics and cleaning products, at the European Center for the Validation of Alternative Methods (ECVAM) Scientific Advisory Committee (ESAC) and at the Japanese Centre for Validation of Alternative Methods. He is the co-developer of the local lymph node assay (LLNA). Current research interests include development of non-animal methods for the identification and assessment of irritants and allergens.

Webinar series sponsored by the American Cleaning Institute (ACI), in collaboration with the Toxicology Excellence for Risk Assessment (TERA) Center, University of Cincinnati & endorsed by the Society of Toxicology (SOT) and the Society for Risk Analysis (SRA)

Asthma webinar sponsors04132016



This webinar series will discuss the advances being made with chemical-induced asthma and the role of clinical, toxicological, and epidemiological research in regulatory and hazard characterization approaches. The webinars are free, but registration is required.

  • Session 1:
    Current Clinical Perspectives in Evaluating Chemical Induced Asthma, or "What Caused My Asthma?"
    February 25, 2016 2pm EST
    Jon Bernstein 
  • Session 2:
    The role of toxicology in asthma hazard assessment
    April 28, 2016 2pm EST
    David Basketter
  • Session 3:
    Environmental contributions to asthma prevalence: Assessing the link between exposure and disease
    June 17, 2016 11am EST
    Judy LaKind
  • Session 4:
    Setting Exposure Limits for Chemical Allergens: Understanding the Challenges
    August 26, 2016 11a.m. EST
    Scott Dotson (NIOSH)
  • Session 5:
    Asthma-specific hazard characterization approaches: A novel approach to a complex problem
    October 21, 2016 11am EST
    Andy Maier